Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1)


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In , he moved to the United States for a research fellowship supported by a grant of the Swiss National Science Foundation and joined Dr. Larry Jameson at Northwestern University in Chicago. After 3 years, he joined the faculty at Northwestern and rose through the ranks to full professor. In , he has moved back to Switzerland to his current position. Kopp has extensive clinical experience in clinical endocrinology with a focus on thyroid cancer and thyroid dysfunction. His research is focusing on the molecular pathophysiology and genetics of thyroid and other endocrine disorders.

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Since he is the Editor-in-Chief of the journal Thyroid, an appointment that reflects his recognized expertise in clinical and basic thyroidology. He has been a member of the thyroid cancer guideline panel of the National Comprehensive Cancer Network from to She is a graduate from the Semmelweis Medical School, Budapest. Her current interests include endocrine tumorigenesis, especially the genetic origin of pituitary adenomas and other endocrine tumour syndromes.

She works on both the clinical characterisation as well as molecular aspects of pituitary diseases and leads a large international consortium to study these rare conditions. She published over original papers and has a Scopus H-index of She shares her time between clinical patient care, clinical research and laboratory based research as well as teaching at undergraduate and postgraduate level. She has served on NIH study sections, and programmatic reviews, and is a board examiner for the American Board of Obstetrics and Gynecology. She has been on the editorial boards of Reproduction, Biology of Reproduction and Clinical and Experimental Reproductive Medicine, and is an associate editor of Journal of Assisted Reproduction.

Her clinical interests are infertility, endocrinology and menopause. He is a physician-scientist having obtained a PhD in reproductive medicine from Monash University in and then he undertook a position as a Visiting Scientist at the University of Washington, Seattle with Dr William Bremner in Upon returning to Australia he has developed clinical and research interests in the fields of spermatogenesis, male fertility regulation and androgen physiology.

He has published more than original papers, reviews and chapters and serves on editorial boards of leading endocrine and andrology journals, and as Editor of the Male Reproduction Section of www. John E. He also serves as Medical Director for two nursing homes. After an internal medicine residency in Johannesburg, he completed a fellowship in endocrinology at the University of California, Los Angeles.

Pediatric Endocrinology - A Lifetime of Personalized Care

He has edited more than 20 books, and published more than papers, with major research emphases on the role of neuropeptides in the modulation of hormonal responses and behavior and on nutrition, geriatric assessments, diabetes and hormones in the elderly. Adrenal Steroid Disorders Group. Department of Pediatrics. Mount Sinai School of Medicine. New York, NY. Leigh Perreault is an Associate Professor of Medicine and Epidemiology striving to transform our current clinical approach to diabetes prevention.

Perreault graduated from the University of Southern California Keck School of Medicine, and completed her residency in Internal Medicine and fellowship in Endocrinology, Metabolism and Diabetes at the University of Colorado Anschutz Medical Campus where she has remained on faculty for the past 16 years. Translation of research for the education of patients and health care providers is one of Dr. John Brunzell. His work as a physician scientist focuses on understanding the causes and consequences of obesity, metabolic syndrome, dyslipidemia, and diabetes in humans.

Rebar received his M.

After his residency, Dr. Rebar continued on at the University of California, San Diego for six years , serving as Associate Professor and Director of the Division of Reproductive Endocrinology for the last two of those years. Rebar is certified by the American Board of Obstetrics and Gynecology in obstetrics and gynecology and subspecialty certified in reproductive endocrinology and infertility.

Rebar has contributed to many books, as well as authored over articles on menopause, fertility, and reproductive endocrinology and has been the Principal or a Co-Investigator on several NIH grants. Frederick R. Parents of young children with type 1 diabetes T1D experience unique, developmental challenges in managing their child's T1D, resulting in psychosocial distress.

Only a small portion of young children reach glucose goals and adherence to diabetes devices that help improve T1D management have historically been low in this population. The purpose of this study is to test four interventions that couple developmentally tailored behavioral supports with education to optimize use of diabetes devices and reduce psychosocial distress for parents of young children with T1D. The study team designed four behavioral interventions, two aimed at improving glucose control and two aimed at optimizing use of diabetes devices.


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The goal of this paper is to describe the behavioral interventions developed for this study, including the results of a pilot test, and describe the methods and analysis plan to test this intervention strategy with ninety participants in a large-scale, randomized trial using a SMART design. A SMART design will permit a clinically relevant evaluation of the intervention strategy, as it allows multiple randomizations based on individualized assessments throughout the study instead of a fixed intervention dose seen in most traditional randomized controlled trials.

In this study, the inControl algorithm developed by TypeZero Technologies was embedded to a commercial Tandem t:slim X2 insulin pump, now called Control-IQ, paired with a Dexcom G6 continuous glucose monitor and tested for superiority against sensor augmented pump SAP therapy. Both groups were physician-monitored throughout the clinical trial.

Continuous glucose monitors CGM can detect asymptomatic hypoglycemia in this population without the need for painful glucose checks. One group of infants was remotely monitored in real-time by research staff during the hospitalization, whereas another group wore a blinded CGM. In both groups, hospital standard-of-care SOC glucose checks were performed. Clinical staff and families were blinded to CGM data.

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Overall, the CGM detected five false-positive alerts and six true-positive alerts for hypoglycemia. Barriers to recruitment included fear of pain with glucose checks, concerns with CGM use, satisfaction with the hospital SOC, personal reasons independent of the study, and lack of interest in participating in research.


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There are variable reports of risk of concordance for progression to islet autoantibodies and type 1 diabetes in identical twins after one twin is diagnosed. We examined development of positive autoantibodies and type 1 diabetes and the effects of genetic factors and common environment on autoantibody positivity in identical twins, nonidentical twins, and full siblings. Of these subjects, 17, identical twins, nonidentical twins, and 16, full siblings were followed for autoantibody positivity or type 1 diabetes for a median of 2. Mobile AP configurations also include a smartphone as computational hub and gateway to cloud applications e.

This International Diabetes Closed-Loop study was designed to demonstrate and evaluate the operation of the inControl AP using different CGMs and pump modalities without changes to the user interface, user experience, and underlying controller. Closed-loop systems titrate insulin based on sensor glucose levels, providing novel means to reduce the risk of hypoglycaemia while improving glycaemic control.

We will assess effectiveness of 6-month day-and-night closed-loop insulin delivery compared with usual care conventional or sensor-augmented pump therapy in children and adolescents with type 1 diabetes. The trial adopts an open-label, multicentre, multinational UK and USA , randomised, single-period, parallel design.

Cognitive, emotional and behavioural characteristics of participants and caregivers and their responses to the closed-loop and clinical trial will be assessed. An incremental cost-effectiveness ratio for closed-loop will be estimated. The findings will be disseminated by peer-review publications and conference presentations. NCT; Pre-results. We tested the safety and performance of the "insulin-only" configuration of the bionic pancreas BP closed-loop blood-glucose control system in a home-use setting to assess glycemic outcomes using different static and dynamic glucose set-points.

This is an open-label non-randomized study with three consecutive intervention periods. Human factors HF testing was conducted using validated surveys. The last five days of each study arm were used for data analysis. Thirteen participants were enrolled with a mean age of 28 years, mean A1c of 7. There was less time View details for DOI We describe a case in which retained wires from a continuous glucose monitor were removed from the abdominal wall and peritoneum of a 6-year-old boy. We highlight a concern for continuous glucose monitor use in children and discuss surgical techniques used to retrieve tiny, mobile objects from complex body cavities.

In September , the U. Food and Drug Administration approved the Medtronic G "hybrid" closed-loop system. In Auto Mode, this system automatically controls basal insulin delivery based on continuous glucose monitoring data, but requires users enter carbohydrates and blood glucose for boluses.

Pediatric Endocrine Self Assessment Program 2017-2018

To track real-world experience with this first commercial closed-loop device, we prospectively followed pediatric and adult patients starting the G system. This was a 1-year prospective observational study of patients with type 1 diabetes starting the G system between May and May in clinic. The primary reason for continuing Auto Mode was desire for increased time in range. At all visits, there was a significant correlation between hemoglobin A1c HbA1c and Auto Mode utilization.


  • Editorial Team!
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  • Research Interests.
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  • While Auto Mode utilization correlates with improved glycemic control, a focus on usability and human factors is necessary to ensure use of Auto Mode. Alarms and sensor calibration are a major patient concern, which future technology should alleviate. A supervised h hybrid closed-loop HCL study was conducted in a hotel setting after a 7-day outpatient standard treatment phase.

    TIER 2 ARTICLE TYPES

    Adults aged years with T1D and HbA1c between 6. Artificial Pancreas AP systems have been shown to improve glycemic control throughout the day and night in adults, adolescents, and children. However, AP testing remains limited during intense and prolonged exercise in adolescents and children.

    We present the performance of the Tandem Control-IQ AP system in adolescents and children during a winter ski camp study, where high altitude, low temperature, prolonged intense activity, and stress challenged glycemic control. Study participants were randomized at each site.

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    Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1) Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1)
    Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1) Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1)
    Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1) Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1)
    Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1) Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1)
    Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1) Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1)
    Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1) Pediatric Endocrinology Board Review (Board Certification in Pediatric Endocrinology Book 1)

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